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1

Oral delivery of curcumin via porous polymeric nanoparticles for effective ulcerative colitis therapy

Chen, Qiubing, Si, Xiaoying, Ma, Lijun, Ma, Panpan, Hou, Meili, Bai, Shuang, Wu, Xiaoshuai, Wan, Ying, Xiao, Bo, Merlin, Didier

Journal:

Journal of Materials Chemistry B

Year:

2017

Language:

english

File:

PDF, 3.09 MB

english, 2017

2

Co-delivery of camptothecin and curcumin by cationic polymeric nanoparticles for synergistic colon cancer combination chemotherapy

Xiao, Bo, Si, Xiaoying, Han, Moon Kwon, Viennois, Emilie, Zhang, Mingzhen, Merlin, Didier

Journal:

Journal of Materials Chemistry B

Year:

2015

Language:

english

File:

PDF, 2.57 MB

english, 2015

3

Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model

Hamed Laroui, Guillaume Dalmasso, Hang Thi Thu Nguyen, Yutao Yan, Shanthi V. Sitaraman, Didier Merlin

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

4

Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy

Zhang, Mingzhen, Xiao, Bo, Wang, Huan, Han, Moon Kwon, Zhang, Zhan, Viennois, Emilie, Xu, Changlong, Merlin, Didier

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 2.85 MB

english, 2016

5

Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis

Arianne L. Theiss, Hamed Laroui, Tracy S. Obertone, Indrajit Chowdhury, Winston E. Thompson, Didier Merlin, Shanthi V. Sitaraman

Journal:

Inflammatory Bowel Diseases

Year:

2011

Language:

english

File:

PDF, 843 KB

english, 2011

6

A2B SiRNA-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduces the Severity of Colitis in a Mouse Model

Hamed Laroui, Guillaume Dalmasso, Pallavi Garg, Lixin Wang, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

7

Inhibition of MDR1 gene expression and enhancing cellular uptake for effective colon cancer treatment using dual-surface-functionalized nanoparticles

Xiao, Bo, Zhang, Mingzhen, Viennois, Emilie, Zhang, Yuchen, Wei, Na, Baker, Mark T., Jung, Yunjin, Merlin, Didier

Journal:

Year:

2015

Language:

english

File:

PDF, 5.26 MB

english, 2015

8

Edible Ginger-Derived Nanoparticles: A Novel Therapeutic Approach for the Prevention and Treatment of Inflammatory Bowel Disease and Colitis-Associated Cancer

Zhang, Mingzhen, Viennois, Emilie, Prasad, Meena, Zhang, Yunchen, Wang, Lixin, Zhang, Zhan, Han, Moon Kwon, Xiao, Bo, Xu, Changlong, Srinivasan, Shanthi, Merlin, Didier

Journal:

Year:

2016

Language:

english

File:

PDF, 7.19 MB

english, 2016

9

Nanoparticle-mediated co-delivery of chemotherapeutic agent and siRNA for combination cancer therapy

Xiao, Bo, Ma, Lijun, Merlin, Didier

Journal:

Expert Opinion on Drug Delivery

Year:

2016

Language:

english

File:

PDF, 688 KB

english, 2016

10

Industrial waste heat recovery using an enhanced conductivity latent heat thermal energy storage

Merlin, Kevin, Soto, Jérôme, Delaunay, Didier, Traonvouez, Luc

Journal:

Year:

2016

Language:

english

File:

PDF, 2.16 MB

english, 2016

11

Oral delivery of nanoparticles loaded with ginger active compound, 6-shogaol, attenuates ulcerative colitis and promotes wound healing in a murine model of ulcerative colitis

Zhang, Mingzhen, Xu, Changlong, Liu, Dandan, Han, Moon Kwon, Wang, Lixin, Merlin, Didier

Journal:

Journal of Crohn's and Colitis

Year:

2017

Language:

english

File:

PDF, 13.03 MB

english, 2017

12

Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration

Abo, Hirohito, Chassaing, Benoit, Harusato, Akihito, Quiros, Miguel, Brazil, Jennifer C., Ngo, Vu L., Viennois, Emilie, Merlin, Didier, Gewirtz, Andrew T., Nusrat, Asma, Denning, Timothy L.

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 4.39 MB

english, 2020

13

ADAM15 to α5β1 integrin switch in colon carcinoma cells: A late event in cancer progression associated with tumor dedifferentiation and poor prognosis

Claire Toquet, Aude Colson, Anne Jarry, Stéphane Bezieau, Christelle Volteau, Pierre Boisseau, Didier Merlin, Christian L Laboisse, Jean-François Mosnier

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 649 KB

english, 2012

14

Extracellular Interaction between hCD98 and the PDZ Class II Domain of hCASK in Intestinal Epithelia

Yutao Yan, Sona Vasudevan, Hang Nguyen, Ulrich Bork, Shanthi Sitaraman, Didier Merlin

Journal:

Journal of Membrane Biology

Year:

2007

Language:

english

File:

PDF, 445 KB

english, 2007

15

Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon

Hamed Laroui, Arianne L. Theiss, Yutao Yan, Guillaume Dalmasso, Hang T.T. Nguyen, Shanthi V. Sitaraman, Didier Merlin

Journal:

Year:

2011

Language:

english

File:

PDF, 2.45 MB

english, 2011

16

Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis

Heloise Gisquet, Honghui Liu, W. C. P. M. Blondel, Agnes Leroux, Clothilde Latarche, J. L. Merlin, J. F. Chassagne, Didier Peiffert, François Guillemin

Journal:

Skin Research and Technology

Year:

2011

Language:

english

File:

PDF, 364 KB

english, 2011

17

Activation of epithelial CD98 glycoprotein perpetuates colonic inflammation

Kucharzik, Torsten, Lugering, Andreas, Yan, Yutao, Driss, Adel, Charrier, Laetitia, Sitaraman, Shanthi, Merlin, Didier

Journal:

Laboratory Investigation

Year:

2005

Language:

english

File:

PDF, 542 KB

english, 2005

18

The oligopeptide transporter hPepT1: gateway to the innate immune response

Charrier, Laetitia, Merlin, Didier

Journal:

Laboratory Investigation

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

19

hPepT1 mediates bacterial tripeptide fMLP uptake in human monocytes

Charrier, Laetitia, Driss, Adel, Yan, Yutao, Nduati, Vivienne, Klapproth, Jan-Michael, Sitaraman, Shanthi V, Merlin, Didier

Journal:

Laboratory Investigation

Year:

2006

Language:

english

File:

PDF, 490 KB

english, 2006

20

ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease

Mosnier, Jean-François, Jarry, Anne, Bou-Hanna, Chantal, Denis, Marc G, Merlin, Didier, Laboisse, Christian L

Journal:

Laboratory Investigation

Year:

2006

Language:

english

File:

PDF, 438 KB

english, 2006

21

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

Wilson, D. Scott, Dalmasso, Guillaume, Wang, Lixin, Sitaraman, Shanthi V., Merlin, Didier, Murthy, Niren

Journal:

Nature Materials

Year:

2010

Language:

english

File:

PDF, 683 KB

english, 2010

22

Tumor necrosis factor-α and interferon-γ increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine

Stephan R. Vavricka, Mark W. Musch, Mikihiro Fujiya, Keri Kles, Laura Chang, Jyrki J. Eloranta, Gerd A. Kullak-Ublick, Ken Drabik, Didier Merlin, Eugene B. Chang

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 358 KB

english, 2006

23

Interferon-γ modulates cAMP-induced mucin exocytosis without affecting mucin gene expression in a human colonic goblet cell line

Anne Jarry, Didier Merlin, Anna Velcich, Ulrich Hopfer, Leonard H. Augenlicht, Christian L. Laboisse

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 870 KB

english, 1994

24

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

Guillaume Dalmasso, Laetitia Charrier–Hisamuddin, Hang Thi Thu Nguyen, Yutao Yan, Shanthi Sitaraman, Didier Merlin

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 3.27 MB

english, 2008

25

Adenosine 2b receptor (A2bR) signals through adenylate cyclase (AC) 6 isoform in the intestinal epithelial cells

Vasantha L. Kolachala, Tracy Sitler Obertone, Lixin Wang, Didier Merlin, Shanthi V. Sitaraman

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2006

Language:

english

File:

PDF, 272 KB

english, 2006

26

Intestinal epithelial CD98: An oligomeric and multifunctional protein

Yutao Yan, Sona Vasudevan, Hang Thi Thu Nguyen, Didier Merlin

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

27

MicroRNAs determine human intestinal epithelial cell fate

Guillaume Dalmasso, Hang Thi Thu Nguyen, Yutao Yan, Hamed Laroui, Shanthi Srinivasan, Shanthi V Sitaraman, Didier Merlin

Journal:

Differentiation

Year:

2010

Language:

english

File:

PDF, 722 KB

english, 2010

28

All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5

Sengthong Chanchevalap, Mandayam O. Nandan, Didier Merlin, Vincent W. Yang

Journal:

Year:

2004

Language:

english

File:

PDF, 307 KB

english, 2004

29

Interferon-γ Increases hPepT1-Mediated Uptake of Di-Tripeptides Including the Bacterial Tripeptide fMLP in Polarized Intestinal Epithelia

Marion Buyse, Laetitia Charrier, Shanthi Sitaraman, Andrew Gewirtz, Didier Merlin

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 535 KB

english, 2003

30

NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis

Anna C. Llewellyn, Jinshi Zhao, Feng Song, Jyothi Parvathareddy, Qian Xu, Brooke A. Napier, Hamed Laroui, Didier Merlin, James E. Bina, Peggy A. Cotter, Mark A. Miller, Christian R. H. Raetz, David S.

Journal:

Molecular Microbiology

Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

31

Nuclear Factor-κB Is a Critical Mediator of Ste20-Like Proline-/Alanine-Rich Kinase Regulation in Intestinal Inflammation

Yutao Yan, Guillaume Dalmasso, Hang Thi Thu Nguyen, Tracy S. Obertone, Laetitia Charrier-Hisamuddin, Shanthi V. Sitaraman, Didier Merlin

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 739 KB

english, 2008

32

Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease

Xiao, Bo, Merlin, Didier

Journal:

Expert Opinion on Drug Delivery

Year:

2012

Language:

english

File:

PDF, 724 KB

english, 2012

33

Prohibitin Is a Novel Regulator of Antioxidant Response That Attenuates Colonic Inflammation in Mice

Arianne L. Theiss, Matam Vijay–Kumar, Tracy S. Obertone, Dean P. Jones, Jason M. Hansen, Andrew T. Gewirtz, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 2.12 MB

english, 2009

34

A2BAR expression in non-immune cells plays an important role in the development of murine colitis

Sarah A. Ingersoll, Hamed Laroui, Vasantha L. Kolachala, Lixin Wang, Pallavi Garg, Timothy L. Denning, Andrew T. Gewirtz, Didier Merlin, Shanthi V. Sitaraman

Journal:

Digestive and Liver Disease

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

35

Constitutive and regulated secretion of secretory leukocyte proteinase inhibitor by human intestinal epithelial cells

Mustapha Si-Tahar, Didier Merlin, Shanthi Sitaraman, James L. Madara

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 308 KB

english, 2000

36

Il-6 induces NF-κB activation that is down-regulated by SOCS-3 in intestinal epithelial cells

Lixin Wang, John Evans, Baljit Walia, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

37

STAT signaling underlies differences between flagellin-induced and TNF-induced epithelial gene expression

Yimin Yu, Hui Zeng, Sean Lyons, Adam Carlson, Didier Merlin, Andrew S. Neish, Shanthi V. Sitaraman, Andrew T. Gewirtz

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

38

397 Colonic STE20-Related Protein Kinase Isoform (SPAK): A Novel Regulator of Intestinal Inflammation

Yutao Yan, Guillaume Dalmasso, Laetitia Charrier-Hisamuddin, Hang Thi Thu Nguyen, Shanthi V. Sitaraman, Didier Merlin

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 112 KB

english, 2008

39

653 Adenosine 2b (A2b)Receptor Knock Out Mice Have Impaired Colonic Motility

Bindu P. Chandrasekharan, Vasantha L. Kolachala, Guillaume Dalmasso, Didier Merlin, Shanthi V. Sitaraman, Shanthi Srinivasan

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

40

825 Reciprocal Effects of Tumor Necrosis Factor Alpha and Prohibitin in Intestinal Epithelial Cells

Arianne L. Theiss, Ngozi I. Okoro, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 75 KB

english, 2008

41

The paneth cell α-defensin cryptdin 3 induces a Ca2+-dependent secretion of IL-8 in model intestinal epithelia

Peter O. Simon, Patricia Lin, Andrew T. Gerwitz, Didier Merlin, Don P. Satchell, Michael E. Selsted, Andre J. Ouellette, James L. Madara, Wayne I. Lencer

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 190 KB

english, 2001

42

Adenosine induces polarized secretion of interleukin-6 in intestinal epithelial cells: Bidirectional epithelial/neutrophil paracrine regulation in model crypt abscess

Shanthi V. Sitaraman, Didier Merlin, Lixin Wang, Michelle Wong, Andrew T. Gewirtz, Mustapha Si-Tahar, James L. Madara

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 371 KB

english, 2001

43

219 Prohibitin (PHB) Is a Novel Antioxidant That Attenuates Colonic Inflammation in Mice

Arianne L. Theiss, Matam Vijay-Kumar, Tracy S. Obertone, Dean Jones, Jason Hansen, Andrew T. Gewirtz, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

44

214 Expression of hPepT1 Aggravates Intestinal Inflammation

Guillaume Dalmasso, Hang Thi Thu Nguyen, Yutao Yan, Mauricio Rojas, Shanthi V. Sitaraman, Didier Merlin

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

45

496 Matrix Metalloproteinase-9 Regulates Intestinal Cell Differentiation By Activating Notch-1

Anupama Ravi, Pallavi Garg, Lixin Wang, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

46

556 Pathogenic Bacteria Transcriptionally Induce Colonic PepT1 Expression – An Implication in Modulating Bacterial-Epithelial Interaction

Hang Thi Thu Nguyen, Guillaume Dalmasso, Yutao Yan, Kim Powell, Shantanu Bhatt, Daniel Kalman, Andrew T. Gewirtz, Shanthi V. Sitaraman, Didier Merlin

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

47

957 Enteric Neuronal Adenosine Receptor 2B (A2BAR) Modulates Murine Distal Colonic Inhibitory Neurotransmission

Bindu P. Chandrasekharan, Vasantha L. Kolachala, Guillaume Dalmasso, Didier Merlin, Shanthi V. Sitaraman, Shanthi Srinivasan

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

48

189 Treatment of Experimental Colitis Using Adenovirus-Directed Expression of Prohibitin

Arianne L. Theiss, Tracy S. Obertone, Indrajit Chowdhury, Winston E. Thompson, Didier Merlin, Shanthi V. Sitaraman

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

49

193 Orally Delivered Thioketal-Nanoparticles Loaded With TNFα-SiRNA Target Inflammation and Inhibit Gene Expression in the Intestines

David S. Wilson, Guillaume Dalmasso, Lixin Wang, Shanthi V. Sitaraman, Didier Merlin, Niren Murthy

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 88 KB

english, 2010

50

258 PepT1 Mediates Transport of the Pro-Inflammatory Tripeptide L-Ala-γ-D-Glu-Meso-Dap in Intestinal Epithelial Cells

Guillaume Dalmasso, Hang Thi Thu Nguyen, Laetitia Charrier-Hisamuddin, Yutao Yan, Hamed Laroui, Shanthi V. Sitaraman, Didier Merlin

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 75 KB

english, 2010

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